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Interoperability is significant in healthcare systems primarily because it enables different healthcare systems to communicate and exchange data effectively. This capability allows for seamless sharing of patient information across various platforms, ensuring that healthcare providers have access to complete and accurate data whenever it is needed.

When healthcare systems are interoperable, they can facilitate better coordination of care, reduce redundancy in tests and procedures, and improve overall patient outcomes. For example, if a patient visits multiple healthcare providers (like specialists, primary care physicians, or emergency departments), the ability to share and access data seamlessly ensures that all parties involved in the patient's care have up-to-date information, which is critical for making informed medical decisions.

Furthermore, interoperability supports compliance with regulatory requirements and enhances population health management by allowing for the aggregation of data across systems, which can be analyzed for trends and outcomes. Thus, the efficient exchange of data driven by interoperability is foundational to achieving integrated, patient-centered care.